Kedu ihe SLU-PP-332 na-eji?
Na nchịkọta, onye na-eme ERR bụ SLU-PP-332 na-arụ ọrụ dị ka ihe ngosi mmega ahụ na-akpali mmemme mmega ahụ aerobic dị oke egwu nke na-eduga na ọtụtụ mgbanwe physiological nke jikọtara ya na mmega ahụ gụnyere mmụba nke eriri oxidative akwara ọkpụkpụ, mmụba nke acid fatty acid, na mmụba nke ntachi obi mmega ahụ.
Zipu ajụjụ gị maka nkọwa ndị ọzọ, pịa email: sales4@faithfulbio.com
Nkowa Obere
SLU-PP-332 bụ obere molekul sịntetị, nke nwere ike na-adịghị ahọrọ estrogen-ejikọtara agonist (ERR), nke nwere mmetụta kachasị ike na ERRα, yana EC50 nke 98 nM. SLU-PP-332 kpalitere mmasị nke nyocha biomedical n'ihi ngwa ya nwere ike na ahụike metabolic na ịme anwansị.
MF: C18H14N2O2
MW: 290.32
CAS: 303760-60-3
Njupụta: 1.20±0.1 g/cm ³ (buru amụma)
Ọnọdụ nchekwa: 2-8°C
Solubility nke DMSO: 2mg/mL, doro anya (ọkụ)
Ọnụọgụ acidity (pKa): 8.44± 0.15 (buru amụma)
Nhazi nke Action
SLU-PP-332 na-arụ ọrụ dị ka agonist ERRα, na-eme ka ọrụ mitochondrial na ike metabolism dị ike. Ọ na-arụ ọrụ dị mkpa n'ịhazi abụba oxidation, glucose metabolism, na thermogenesis, na-eme ka ọ bụrụ onye nwere ike ime ọgwụgwọ ọrịa metabolic. Ngwakọta ahụ na-ejikọta na ngalaba ligand-binding nke ERRα, na-eme ka nhazi ya na-arụ ọrụ na-eme ka mmekọrịta ya na protein coactivator, karịsịa PGC-1a (peroxisome proliferator-activated receptor gamma coactivator 1-alpha).
Nyocha na Ngwa
A nwalere SLU-PP-332 n'ọtụtụ ọmụmụ ihe ọmụmụ, gụnyere ike ya: Melite ọrịa metabolic site n'ịkwalite arụmọrụ mitochondrial. Welite mmega ahụ-mimetic mmetụta na akwara anụ ahụ. Weghachite arụ ọrụ mitochondrial metụtara afọ. SLUPP-332 nwere ike ịkwalite ọrụ mitochondrial na iku ume cellular, na-abawanye ụdị IIa oxidized skeletal fibers, ma welie mmegide mmega ahụ nke ahịrị akwara skeletal. SLU-PP-332 nwere ike iji mee ihe na nyocha nke ọrịa metabolic na imeziwanye ọrụ anụ ahụ, a pụkwara iji ya mee ka nsogbu metabolic na ịka nká dịkwuo mma.
Mmetụta Ndu
Ọrịa Metabolic na oke ibu
Nnyocha na ụdị anụmanụ egosila na SLU-PP-332 na-eme ka mmetụta insulin dịkwuo mma ma na-ebelata adiposity, na-atụ aro ike ya dị ka ọgwụ mgbochi oke ibu. SLU-PP-332 emepụtara:
18-24% mbelata ibu ahụ.
30-35% mbelata na oke anụ ahụ adipose ọcha.
40% mmụba na nnabata glucose.
25-30% na-ebelata ọkwa insulin na-ebu ọnụ.
Mbelata dị ịrịba ama na hepatic steatosis na mbufụt.
Kedu uru SLU PP dị?
SLU-PP-332 bụ ọgwụ na-eṅomi mmetụta nke mmega ahụ, na-eduzi mmefu ike na-abawanye na metabolism abụba dị nso. mmalite mmega ahụ. Onye ọrụ a na-eme ka usoro metabolic dị n'okike nke na-emeghachi omume na mmega ahụ n'ụzọ doro anya, na-ebute mmefu ume ike, yana mgbakwunye abụba anụ ahụ.
SLU-PP-332 ọ na-arụ ọrụ?
Nchọpụta nke mbụ lekwasịrị anya na ụmụ oke dị arọ ma kpughee ụfọdụ ọmarịcha nsonaazụ. Ụmụ oke ejiri SLU-PP-332 mee ihe nwere ike ịgba ọsọ maka 70% ogologo na 45% karịa ndị otu ha na-adịghị agwọ ọrịa. Nke ahụ dị ka ịga site n'ịme ya n'akụkụ ngọngọ gaa na njikere na mberede maka ọkara marathon!
Kedu ihe mmetụta SLU-PP-332 nwere?
Mmetụta nwere ike ime: Mmetụta ndị a na-ahụ anya gụnyere hyperthermia dị nro, ụbara ọnụ ọgụgụ obi, na mgbanwe na-adịte aka na enzymes imeju na ọmụmụ anụmanụ.
Ego ole bụ SLU-PP-332?
| Iberibe Ibu | price |
| 1g | USD 50 |
| 5g | USD 239 |
| 10g | USD 388 |
| 50g | USD 1,458 |
| 100g | USD 2,498 |
Biko gwa anyị adreesị mbupu zuru ezu ka anyị nwee ike iziga gị ụgwọ mbupu.
Zipu ajụjụ gị maka nkọwa ndị ọzọ, pịa email: sales4@faithfulbio.com
Ọdịnihu dị n'ihu
Nnyocha na SLU-PP-332 na ndị modulators ERR metụtara na-aga n'ihu na-agbasawanye na mpaghara ọgwụgwọ ọhụrụ:
Neurodegeneration: Ọmụmụ ihe mbụ na-atụ aro ngwa nwere ike na ọrịa Alzheimer na ọrịa Parkinson site na ọrụ mitochondrial ka mma.
Metabolism ọrịa kansa: Nnyocha n'ime ọrụ nke akara ERR na ike ike tumor na ngwa ọgwụgwọ nwere ike.
Nnyocha ogologo ndụ: Nchọgharị nke ịgbalite ERR dị ka ihe nwere ike ime iji gbasaa ogologo ahụike.
Usoro ọgwụgwọ ahaziri onwe ya: Mmepe nke biomarkers iji chọpụta ndị ọrịa nwere ike ịzaghachi usoro ọgwụgwọ ezubere iche ERR.
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